Items of Cosmetic dermatology

Laser Hair removal

LAC

Iontophoresis (イオン導入) Skin Beauty Care

【Principle】

Our skin surface has a function of isolation and protection, which results in inability for
active ingredients that are smeared onto our skin to permeate into deeper skin layers. Ion-importing is
effective in aiding water-soluble effective ingredients to penetrate this protective layer and reach the deeper
skin layers. There have been reports pointing out that:ion-importing achieves permeability effects more than 4
times that of simple smearing.

【Treatment Course】

One import treatment every 1-2 weeks is recommended. One treatment every month can achieve
persistent skin beauty effects.

※EX: Possible sunburn during vacation… Undergoing minimize the
damage caused by UV light.

※EX: Necessity for quickly achieving whitening effects of skin
before a wedding ceremony. Once to multiple times a week depending on the location and skin condition. Those
interested should consult with the physician.

【Treatment effects】

Ingredients such as high concentration vitamin, tranexamic acid, vitamin C,
multi-vitamin,etc. will not only act on the surface of the skin, but will enter the basal layer of the skin
and deep into the dermal layer. Active ingredients are chosen according to the symptoms, using ion-importing
treatment to provide significant effects and alleviate to acne, promote elastin and collagen synthesis,
suppress melanin synthesis or facilitate excretion of deposited pigments, and remove reactive oxygen species
(causes aging), etc.

【Patients not able to undergo treatment】

• Pregnant or lactating individuals
• Individuals wearing cardiac pacemakers
• Individuals with other implantable metallic or mechanical devices

Sonophoresis Skin Care

Ingrown Nail Bracing Technique 3TO (VHO)

Although many people suffer from ingrown toenails that sink deep into the
paronychium, or “pincer nails” that bend abnormally towards the medial side, there has currently been no
optimal treatment for such conditions. “3TO (VHO) nail bracing technique” utilizes the human body’s own
healing abilities to treat even conditions where the nail has sunk deep into the nail bed. The treatment is
currently the best option as the patient will able to shower or exercise on the day when treatment is
completed, and it will not affect daily activities.
※ If the affected area has tinea pedis or infection,please undergo treatment
first before undergoing this treatment.

☆The hook hangs on the nail,not on the skin,
thus doesn’t cause pain. There is no need for anesthesia.

☆The fixated wire will move forward along with
the growing toenail, so the hook’s location will have to be adjusted every 3 months after surgery. The
toenail will slowly correct into a normal condition within 6 months to a year.

※Medical insurance does not provide for this
treatment as this is a selfpaid treatment.

【Advantages of the Ingrown Nail Bracing
Technique 3TO (VHO)】

3TO (VHO) ingrown nail bracing technique is currently
the method with least burden.

It has good flexibility to accommodate to any kind of situation.

On-site adjustment of the wire’s length
and curvature in accordance to different types of ingrown nails’ shapes and surrounding conditions.

Painless and
sanitized

Easily recover to the natural nails

Correction is often completed after 3
months if there are no further complications.

※ Ingrown nails can be affected by daily
factors such as gait and shoes, and may recur. It is important to avoid factors that may cause ingrown nails
even after the wire is installed.

Ingrown Nail Bracing 3TO (VHO)

Ingrown NailBracing	(1unit)：￥10,780
Wire Adjustment	￥5,280
Follow-up Charge	￥1,100

Derma Pen 4

The Derma Pen 4 treatment in our hospital uses ultra-fine needles thinner than hair to create numerous
small pores on the skin surface to improve natural skin healing and achieve aesthetic effects.This treatment
promotes metabolism which can increase dermal collagen, hyaluronic acid and elasticity.
The effects include prevention and alleviation of large pores, loose skin pores, keratosis pilaris, scarring and
uneven skin texture caused by acne inflammation. In addition, it can also decrease fine wrinkles,
hyperpigmentation.

As symptoms and treatment results vary from person to person, expected results
may be achieved in one treatment in some individuals, but several treatments may be needed to achieve expected
results in other individuals.

【Treatment Intervals】

Once a month for around 4-6 sessions (determined based on individual results)

【Side effects】

After surgery, point-like needle mark may be experienced, and skin reddening,petechiae, or
local swelling may occur. These symptoms usually subside after a few days but may require a longer time up to
one week in certain individuals.

【Precautions】

Do not rub the treated site after treatment. Face washing or cosmetic application can be
carried out after 12 hours. At the same time, please avoid stimulating skincare products and maintain
cleanliness at the treated site as much as possible.

【Patients with the following conditions cannot undergo this treatment】

Allergy to lidocaine and metals, shingles, pregnancy, breast-feeding period, wounds,or
inflammation present at other sites.

Massage Peeling

In contrast to normal exfoliating peel, the penetration of deep skin withnon-exfoliating compound
formulations will not only promote collagen synthesis and increase skin elasticity but also improve skin with
large pores.PRX-T33 is different from other exfoliating
treatments as it does not cause keratin peeling but can improve skin elasticity, decrease pigmentation, and
improve acne scars.

In addition to trichloroacetic acid (TCA) and hydrogen peroxide
(H₂O₂), PRX-T33 also contains
kojic acid that can brighten skin. Therefore, it can simultaneously improve melasma and freckles to achieve
whitening effects.

【Treatment Course】

The usual standard is 5 treatments every 2-3 weeks. It is recommended that maintenance
treatment be carried out every 1-2 months after the skin has rested for 1 month. (Based on skin condition, we
may recommend a set of standard treatment before maintenance)

【Precautions】

During surgery, you may experience burning or prickling pain. After treatment, the skin will
become red, but this usually resolves within1-2 days and may require one week in some cases. During this
period, please do not use alcohol-containing cosmetics and facial scrubs.
Pregnant and breast-feeding women cannot undergo this treatment. Patients with allergic skin or who develop
dermatitis frequently must select a suitable time to undergo this treatment

Velvet Skin Regeneration (Derma Pen 4 + Massage Peeling)

This is a method that combines DermaPen4 with massage peeling and is used to treat acne scars, scars, and
stretch marks. The subject can feel an increase in elasticity and firmness in the deep skin layer. In order to
induce the repair at the deep skin layer, a microneedler is used to create numerous pores on the skin surface. The
skin produces large amounts of collagen through its regeneration and self-healing ability to heal these pores.
Collagen will shrink pores and improve acne scars to increase skin firmness and elasticity.

PRX-T33 Massage peel is
applied on the skin with highly dense pores and can penetrate to the dermis. Under this synergistic effect, skin
firmness and elasticity rapidly increase,causing it to be like velvet skin.

【Treatment cycle】

Once every 4-6 weeks (it is recommended that multiple treatments be carried out.
However, efficacy varies from individual to individual)

【Contraindicated Patients】

• Patients with a keloid constitution
• Patients with bleeding disorders
• Patients who are allergic to lidocaine
• Patients with conditions deemed by the physician to be unsuitable for this treatment

Botox

Principles
Botox Vista® is a drug that uses C.
botulinum type A as its active ingredient. Between nerves and muscles, the chemical transmitter, acetylcholine, is
released, and transmits nerve stimulation to the muscle, causing them to contract.
Botox VISTA® is injected into tense muscles to relax them and can improve facial wrinkles. Botox Vista also blocks
the nerve stimulation of sweat　secretion, thus inhibiting the function of sweat glands.

Applicable symptoms

• Facial wrinkles (between the eyebrows, corner of the eye)
• Hyperhidrosis (underarms) ※ insurance is applicable

【Points to note】

• Pregnant women and women who are breast-feeding should not　use the drug; please practice contraception
  until the end of　the second menstruation after the last injection.Men must practice contraception for at
  least three months during the course of injection.
• People with neuromuscular disorders cannot receive this treatment.In addition, people taking antiplatelet
  drugs are prone to internal bleeding, please pay special attention.
• Botox Vista® is approved by Ministry of Health, Labour and Welfare of Japan as a highly safe drug.However,
  there’s no guarantee you won’t develop an unknown infection after the injection.
• A small number of people will develop antibodies in their bodies that will weaken the effect of the
  treatment.

Hydra Facial

Hyperhidrosis treatments provided by our hospital

The purpose of sweating is to prevent excessively high body temperature as sweating can regulate body temperature.
However, many people with a hyperhidrotic constitution find that their daily lives are affected. This is known as
hyperhidrosis.
Hyperhidrosis can be classified as primary hyperhidrosis in which the etiology is unknown or secondary hyperhidrosis
that is caused by diseases or drugs. Our hospital provides the following treatments for primary hyperhidrosis.

Ointments (topical drugs)

It is medically proven that aluminum chloride can cover the sweat glands in the stratum corneum to reduce sweating.
Results will slowly appear when the patient applies the ointment continuously every day. As the duration of the
effect is short, sweating will occur once topical application is discontinued. The ointment can be applied at all
sites on the body and is not limited to the limbs and armpits. As this ointment is currently not approved for
insurance coverage, our hospital has 10% to 30% aluminum chloride ointments for patients to use.

Injection drugs (Botox therapy)

Botox therapy is the axillary injection of natural protein drugs extracted from Clostridium botulinum. This toxin
works by inhibiting the secretion signals by the sympathetic nervous system on the sweat glands to achieve its
antiperspirant effects.
There is no need to worry whether injection of botulinum toxin will result in infection. This drug can only be
covered by insurance payment when a diagnosis of severe axillary hyperhidrosis is made by the doctor The treatment
effects varies amongst people and one injection can usually last for around 4 to 6 months.

Oral medications

There is one oral medication that is covered by insurance, which is Probanthine. Effects are observed around 1 hour
after administration and persists for around 5 hours. As this drug may cause other side effects such as mild
constipation, it cannot be taken for long periods. Patients with glaucoma or prostate hypertrophy cannot use this
drug as well. Please seek consultation at our hospital if you do not wish to be troubled by hyperhidrosis on the
head and face.

Treatment for Rosacea

Flagyl (metronidazole) topical ointment is a standard treatment method for rosacea in the world but is not amongst
drugs covered by insurance in Japan. Our hospital has a dedicated self-paid formula. This is a slow-acting drug that
has good therapeutic efficacy. Even though its effector mechanisms are still unclear, it is widely acknowledged that
the ointment has anti-inflammatory and immunosuppressive effects. Its hydrophilic ointment base can alleviate
inflammation and heat sensation.